Histopathological Patterns Of Testicular Biopsy In Male Infertility In Khyber Pakhtunkhwa, Pakistan

Original Article

Abstract

Objective: Histopathological alterations found in the testicular biopsies of male infertiles.
Materials & Methods: This inscriptional study was carried out between July 2012 and June 2014 in the urology
and pathology departments of North West General Hospital and Research Center Peshawar and Rehman Medical
Institute Peshawar.There were a total of 71 infertile patients enrolled in this study. The couples underwent a thorough
clinical history, physical examination, semen analysis, and hormone analysis before having testicular biopsy. In the lab,
biopsies were fixed, processed, stained, and mounted. There were seven histopathological patterns classified. Testicular
biopsies were evaluated using the Johnson Score (1–10).
Results: This study showed (36.62%) Sertoli cell only syndrome, (62%) maturation arrest, and (19.72%) normal
spermatogenesis. Nonobstructive azoospermia cases: 73.24% Obstructive azoospermia cases: 26.76%.
Conclusion: The most common pattern in our research is germ cell aplasia or Sertoli cell syndrome, which accounts
for 36.62% of all cases.
Key Words: FSH, LH, azoospermia, spermatogenesis & infertility