Frequency Of Helicobacter Pylori Infection And Its Prevalence Across Gender In District Nowshera Kpk

Original Article

Abstract

Background: Helicobacter pylori lives in the stomach’s gastric mucosa. One of the most genetically diverse bacterial
species, it infects billions worldwide. There is evidence that the bacterium that causes stomach cancers, peptic ulcers,
chronic gastritis, and gastric malt lymphoma has a sociodemographic and geographic pattern. Despite infections not
necessarily dangerous, their frequency is higher in Africa than in other areas, according to research. The specific processes
of H. pylori transmission could be clearer. However, poor hygiene, crowded living situations, unclean water, and contaminated surroundings constitute dangers. Oral-oral, fecal-oral, and person-to-person transmission are possible, with
or without transitional stages, during diarrhea or vomiting. The organism’s spread may also be linked to contaminated
water, such as municipal tap water.
Objectives: To evaluate the frequency of H. pylori infection in District Nowshera and to determine the prevalence
of H. Pylori across genders.
Study design: A Cross-sectional observational study
Duration and place of study: Department of Biochemistry Nowshera Medical College & Qazi Hussain Ahmed
Medical Complex Nowshera from January-December 2017
Methods: Patients from 13 to 54 years old, both male and female, were included in this research. One hundred eight
samples were taken from individuals chosen for further H. pylori research.
Results: The patients ranged in age from 13 to 54 years old, with a mean age of 33.54±8.496. Out of 108 patients, the gender distribution was as follows: male patients comprised 55.6% of the patient population, while female
patients comprised 44.4%. Out of 108 patients, 45 had H. pylori infection, or 41.7%. In contrast, 63 patients did
not have H. pylori infection, or 58.3%. The proportion of patients with H. pylori was 41.7%; the number of men
with the infection was 27.8%, and the number of females was 13.7%. There were 58.3% negative instances, with
27.8% of the cases being male and 30.6% being female.
Conclusion: According to the study, male patients are more likely than female patients to have an H. pylori infection.
Keywords: Helicobacter pylori, Gastritis, Gastric and duodenal ulcers, Raynaud’s syndrome, Migraine.