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Relationship Of Serum Leptin With Coronary Artery Disease

Abstract



Background: Leptin a protein produced in adipose tissue is related to obesity/adiposity and coronary artery disease( C A D )
Objectives: To compare serum leptin in C A D patients with control Patient: We studied two hundred adult Individuals consisting of equal number of patients and normal control.
Results: The serum leptin level is 17.57+4.39 S D in C A D patients as compared to normal control 6.82+3.05 S D . It is high in 109 in obese as compared to normal BMI 24 ( P=<.05) irrespective of cardiac status .It is high (11.75+5.64 ) in female patients as compared to (11.07+4.77 S D ) male patients.
Conclusion: The serum leptin level in C A D patients is significantly raised as compared to normal control. It is significantly high in obese patients. It is significantly high in female patients as compared to male patients .Higher studies are needed to study it’s athrogenic potential.Anti obesity measures are needed to prevent CAD

Salma Raheem

Department of Biochemistry, Bacha Khan Medical College, Mardan, Pakistan

Muhammad Siyar

Department of Biochemistry, Bacha Khan Medical College, Mardan, Pakistan

Muhammad Khalid

Department of Physiology, Bacha Khan Medical College, Mardan, Pakistan

Muhammad Israr

Department of Biochemistry, Bacha Khan Medical College, Mardan, Pakistan

Zarmina Farhan

Department of Biochemistry, Bacha Khan Medical College, Mardan, Pakistan

Muzahir Jan

Department of Biochemistry, Bacha Khan Medical College, Mardan, Pakistan

Farhan Akram

Department of Biochemistry, Bacha Khan Medical College, Mardan, Pakistan

Salma Raheem

Department of Biochemistry, Bacha Khan Medical College, Mardan

Email: salmarahim59@gmail.com

Mobile: 0336-0404333