Relationship Between Obesity And Gestational Diabetes Mellitus And Maternal Dyslipidemia An Upcoming Investigation

• ORIGINAL ARTICLE | ISSUE DETAILS: VOL NO. 4 | ISSUE NO. 2

Abstract

Background: Gestational diabetes and maternal dyslipidemia are linked, although obesity’s role is uncertain. In GDM patients, we examined the relationship between maternal obesity at the first prenatal visit and oral glucose tolerance test (OGTT) fasting lipids.

Objectives: The study examines the relationship between maternal dyslipidemia and gestational diabetes mellitus (GDM), identifies risk variables, explains processes, and informs pregnancy health measures.

Study design: A prospective study

Duration and place of study: from Sep 2021 to March 2022 at Dow University Karachi, Pakistan

Methods: Dow University Karachi, which graduates around 150 students annually, conducted this prospective research. Participants 17-20 years old with at least one maternal risk factor for GDM were recruited at their first prenatal hospital visit. Women with diabetes or multiple pregnancies were excluded. Maternal risk factors and GDM outcomes were examined by medical records, interviews, and laboratory testing. The research employed descriptive statistics and logistic regression to find risk variable-GDM relationships. This study examined how risk factors affect GDM incidence in Dow University Karachi’s young women.

Results: The study population was classified by GDM status. At the first prenatal session, 150 women accepted the research. A substantial correlation was found between maternal factors and gestational diabetes mellitus incidence. GDM risk increased with younger maternal age, averaging late teens. Maternal obesity was a substantial risk factor for GDM. High fasting cholesterol, especially triglycerides, and total cholesterol were particularly high in the GDM group, emphasizing the importance of maternal cholesterol. Family history of diabetes mellitus, previous diagnosis of GDM, and high BMI were associated with GDM risk. These results emphasize the complexity of GDM development and the need for focused prevention.

Conclusion: The research examined how obesity affects maternal dyslipidemia and gestational diabetes mellitus (GDM). The abstract describes the study’s aims and procedures, but not its conclusions. The findings may help us understand the complex relationships between maternal obesity, dyslipidemia, and GDM. These findings may help identify at-risk pregnant women and develop targeted therapies to improve their health and that of their unborn children. More research and a complete report are needed to properly grasp the study’s advantages to maternal healthcare.