Maternal Dyslipidemia And Obesity/Gestational Diabetes Mellitus Are Associated An Upcoming Investigation

• ORIGINAL ARTICLE | ISSUE DETAILS: VOL NO.4 | ISSUE NO. 1

Abstract

Background: Maternal dyslipidemia and gestational diabetes are known to be associated, however it is unknown how obesity plays a role in this interaction. We examined the relationship between fasting lipids at the oral glucose tolerance test (OGTT) in women diagnosed with GDM and maternal obesity at the first prenatal visit. Objectives: The study aims to investigate the relationship between maternal dyslipidemia and gestational diabetes mellitus (GDM), pinpoint risk factors, elucidate procedures, and provide guidance for therapeutic treatments aimed at improving the health of expectant mothers.

Study design: A prospective study

Duration and place of study: from jan 2022 to jan 2023 at Dow University Karachi, Pakistan

Methods: This prospective study was undertaken at Dow University Karachi, which has an annual delivery rate exceeding 150 pupils. At their first prenatal hospital visit, participants who were between the ages of 20 and 45 and had at least one maternal risk factor for GDM were enlisted. Pregnant women with diabetes mellitus or those who have had several pregnancies were excluded. To investigate maternal risk factors and GDM outcomes, laboratory tests were carried out, interviews were done, and medical records were examined. In the statistical analysis, logistic regression and descriptive statistics were used to find relationships between risk factors and the development of GDM. The purpose of this study at Dow University Karachi was to ascertain the impact of risk factors on the incidence of GDM in young women.

Results: The features of the research population were classified according to the presence or absence of GDM. 150 women consented to participate in the research during their first prenatal visit. The study’s findings demonstrated a strong correlation between maternal traits and the prevalence of gestational diabetes mellitus (GDM). An average of late adolescence and a younger mother age indicated a greater risk of GDM. It was noted that maternal obesity was prevalent among individuals who had GDM and that it posed a significant risk. GDM risk was linked to specific risk factors like a family history of diabetes mellitus, a prior diagnosis of GDM, and a high body mass index. Additionally, elevated fasting cholesterol, particularly triglycerides, and total cholesterol were particularly high in the GDM group, highlighting the importance of maternal cholesterol. These results emphasise the complexity of GDM development and the need of focused preventive measures.

Conclusion: The  study looked at the link between maternal dyslipidemia and gestational diabetes mellitus (GDM), emphasizing the impact obesity plays in this interaction. Although the study’s goals and methods are explained in the abstract, the findings are regrettably not shared. However, the study has the potential to further our knowledge of the intricate interactions among maternal Obesity, dyslipidemia, and GDM. These results may have significant ramifications for identifying pregnant women who are at risk and creating focused treatments to enhance the health of pregnant moms and their unborn children. The study’s benefits to maternal healthcare must be fully appreciated by more Study and a comprehensive presentation of the findings.