Histopathological Patterns Of Testicular Biopsy In Male Infertility In Khyber Pakhtunkhwa, Pakistan

• ORIGINAL ARTICLE | ISSUE DETAILS: VOL NO.1 | ISSUE NO. 1

Abstract

Objective: Histopathological alterations found in the testicular biopsies of male infertiles.

Materials & Methods: This inscriptional study was carried out between July 2012 and June 2014 in the urology and pathology departments of North West General Hospital and Research Center Peshawar and Rehman Medical Institute Peshawar.There were a total of 71 infertile patients enrolled in this study. The couples underwent a thorough clinical history, physical examination, semen analysis, and hormone analysis before having testicular biopsy. In the lab, biopsies were fixed, processed, stained, and mounted. There were seven histopathological patterns classified. Testicular biopsies were evaluated using the Johnson Score (1–10).

Results: This study showed (36.62%) Sertoli cell only syndrome, (62%) maturation arrest, and (19.72%) normal spermatogenesis. Nonobstructive azoospermia cases: 73.24% Obstructive azoospermia cases: 26.76%.

Conclusion: The most common pattern in our research is germ cell aplasia or Sertoli cell syndrome, which accounts for 36.62% of all cases.