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Objective: This study examined the risk of lifetime and present methamphetamine-induced psychosis in dependent individuals. The relationship between methamphetamine-induced psychosis and mental co-morbidity was examined.
Study design : A Cross-sectional study
Duration and place of study : tertiary care hospital of Peshawar from January 2022 to January 2023
Methods: This Cross-sectional study done simultaneously at a Peshawar Tartary care hospital from January 2022 to January 2023. The Mini International Neuropsychiatric Interview (M.I.N.I.) was used to interview DSM-IV-diagnosed methamphetamine users for psychosis and other Axis I psychiatric disorders. Social demographics and drug use history were acquired via interviews or medical records.
Results: There was a history of psychotic symptoms in 65 (45.4% of the total) participants, and 23 (15.6% of the total) patients at the present time. After adjusting for other covariates, there was a substantial association between heavy methamphetamine use, childhood methamphetamine-induced psychosis, and co-morbid major depressive disorder (n-24, 16.2%), bipolar disorder (n-6, 5.8%), and antisocial personality disorder (n-14, 10.8%). The only variables linked to present psychosis were major depressive illness (n-6, 5.8% of the population) and antisocial personality disorder (n-4, 4.2% of the population).
Conclusion: this study sheds light on the interplay between methamphetamine use, psychosis, and co-morbid mental disorders. Early detection and integrated treatment approaches are vital for mitigating the adverse effects of substance abuse and improving mental health outcomes in affected individuals.
Muhammad Arif
Department of E.N.T Hayat Abad Medical Complex Peshawar
Allah Noor
Department of E.N.T Hayat Abad Medical Complex Peshawar
Mohammad Khalid Khan
Department of Community medicine, Gajju Khan Medical College, Swabi - Pakistan
Muhammad Sajid
Department of Pharmacology, Gajju Khan Medical College, Swabi - Pakistan
Allah Noor
Department of E.N.T, Hayatqbad Medical Complex Peshawar
Email: dr.allahnoor2015@gmail.com
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