Notifications :

Notify a list of Editors to work full time for the Journal of Bacha Khan Medical College (JBKMC): Dated 28 Dec, 2017

Start a research journal in the name of 'Journal of Bacha Khan Medical College (JBKMC)': Dated 20 Dec, 2015

Evaluation Of Ciprofloxacin And Ceftriaxone's Efficacy In The Treatment Of Gonorrhoea

Abstract



Introduction: A very infectious bacterial illness that may infect both men and women via sexual contact is gonorrhea, a serious public health hazard. It is among the most ancient sexually transmitted infections (STDs), and Neisseria is the cause. Rarely, gonorrhea may also result in pharyngeal, ocular, articular, and dermatological conditions in addition to its predominant urogenital signs and symptoms. Gonorrhea has been treated with various antibiotics,including spectinomycin, cephalosporins, tetracyclines, macrolides, sulpha medicines, and fluoroquinolones. Some of these medications are no longer used to treat gonorrhea due to an increase in resistant infections.
 
Objectives: This research compared the efficaciousness of Ceftriaxone and ciprofloxacin in managing gonococcal infections.
 
Study Design: A- Observational- Study Place And Duration of Study: The study was conducted in New Gulail Polyclinic, Saudi Arabia, from January 2003 to March 2004.
 
Methods: With the institutional Ethical Committee’s consent, 200 patients received Ceftriaxone and ciprofloxacin to treat gonorrhea. Enrolling the patients included the use of a purposeful sampling approach. Every patient was divided into two groups of 100 individuals, each at random. Group B received a single intravenous dose of 500mg of Ceftriaxone Injection, whereas Group A received a 500 mg tablet of Ciprofloxacin. After five days, all of the patients had follow-up examinations, and their lab and clinical test results were documented and evaluated.
 
Results: Patients in Group A (n=100) receiving ciprofloxacin demonstrated 80% full response, 9% partial response, and 11% showed no improvement on the fifth day after therapy. On the other hand, patients taking ceftriaxone in Group B (n=100) had 90% complete responses, 4% partial responses, and 6% no responses at all. To sum up, Ceftriaxone treated gonorrhea more well than ciprofloxacin. It is recommended that all patients get a follow-up examination to confirm the whole course of therapy for gonorrhea after taking a single antibiotic dosage.

Shams Ur Rahman

Department of Medicine, Gajju Khan Medical College Swabi, Pakistan

Mohammad Iftikhar Adil

Department of Pharmacology, Gajju Khan Medical College Swabi, Pakistan

Tariq Zubair

Department of Medicine, Gajju Khan Medical College Swabi, Pakistan

Surrya Israr

Department of Gynecology, Gajju Khan Medical College Swabi, Pakistan

Mohammad Bilal

Department of Ophthalmology, Gajju Khan Medical College Swabi, Pakistan

Prof. Zia Muhammad

Department of Ophthalmology, Bacha Khan Medical College, Mardan, Pakisan

Email: eyesurgzia@gmail.com

Mobile: 0303-8577188